The effect of acute and chronic exercise on steroid hormone fluctuations in young and middle-aged men

Sellami, Maha, Dhahbi, Wissem, Hayes, Lawrence ORCID: https://orcid.org/0000-0002-6654-0072 , Kuvacic, Goran, Milic, Mirjana and Padulo, Johnny (2018) The effect of acute and chronic exercise on steroid hormone fluctuations in young and middle-aged men. Steroids, 132 . pp. 18-24.

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Abstract

The current study examine the effects of combined sprint and resistance training on serum total testosterone (TT), sex-hormone-binding globulin (SHBG) and cortisol (C), at rest, and in response to the Wingate Anaerobic-Test (WAnT) in 21 and 41years old men. Forty moderately-trained men were randomly assigned to a young trained (YT), young control (YC), middle-aged trained (MAT), and middle-aged control (MAC) group. Before (P1), and after (P2) training, blood samples were collected at rest and after exercise. At P1, higher C and lower TT was observed in middle-aged groups compared to younger ones (P<0.05). At P2, basal TT increased significantly (P<0.05) in MAT and the age-difference was absent between trained groups (P>0.05). Basal SHBG decreased significantly in YT at P2 (P<0.05) but did not change in other groups from before to after training (P>0.05). Free-testosterone was significantly (P<0.05) higher in young compared to middle-aged groups at P1, but at P2, this age-related difference disappeared between YT and MAT (P>0.05). C post-WAnT increased significantly for MAT only (P<0.05) at P2, whilst no significant changes were observed in the other three groups (P<0.05) at P2. In contrast, resting levels of C did not change in all groups at P2 (P>0.05). The current study demonstrates that this training intervention may help increase steroids hormones in middle-aged men and counteract the negative effect of age on TT and free testosterone.

Highlights: Total testosterone, cortisol and SHBG increase with the exercise intensity; Intensive training increase basal testosterone levels in middle­-aged men; Intensive training reduces age effect in testosterone levels in middle­-aged men; Intensive training does not alter basal SHBG and cortisol levels in middle­-aged men.

Item Type:	Article
Journal / Publication Title:	Steroids
Publisher:	Elsevier
ISSN:	1878-5867
Departments:	Academic Departments > Medical & Sport Sciences (MSS) > Sports and Physical Activity
Depositing User:	Anna Lupton
Date Deposited:	07 Feb 2018 12:00
Last Modified:	12 Jan 2024 19:32
URI:	https://insight.cumbria.ac.uk/id/eprint/3584

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