Influence of maternal factors and mode of induction on labour outcomes: a pragmatic retrospective cohort study

Jonker, Leon and Memon, Fouzia (2018) Influence of maternal factors and mode of induction on labour outcomes: a pragmatic retrospective cohort study. Journal of Obstetrics and Gynaecology . Item availability may be restricted.

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Official URL: https://doi.org/10.1080/01443615.2018.1441814

Abstract

Since recent research indicates that other modalities are at a minimum non-inferior to the NICE-recommended hormonal agent prostaglandin E2 (PGE2), a retrospective cohort study was conducted on 1971 consecutively induced singleton pregnancies. The multinominal regression showed that the odds ratio (OR) for vaginal delivery with balloon-mediated labour induction (84% vaginal deliveries; OR 1.6; 95% CI 0.7–3.5) is similar to the PGE2 agents propess (81%; OR 1.2; 95% CI 0.68–1.98) and prostin (79%; OR 0.99; 95% CI 0.55–1.79) when using a triple multi-agent induction as a reference. On the other hand, combining the propess and prostin (60% vaginal deliveries; OR 0.45; 95% CI 0.21–0.96) and attempting quadruple combinations of the induction modalities (56%; OR 0.37; 95% CI 0.16–0.85) yields significantly poorer outcomes. However, compared to the known factors associated with increased caesarean section rates, such as an increased maternal age, nulliparous pregnancies and a history of caesarean section, the differential impact of different induction modalities appears as less pronounced.

Item Type: Article
Journal or Publication Title: Journal of Obstetrics and Gynaecology
Publisher: Taylor & Francis
ISSN: 1364-6893
Departments: Marketing & Student Recruitment
Depositing User: Anna Lupton
Date Deposited: 02 Mar 2018 13:42
Last Modified: 13 Dec 2018 13:27
URI: http://insight.cumbria.ac.uk/id/eprint/3646

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