Influence of maternal factors and mode of induction on labour outcomes: a pragmatic retrospective cohort study

Jonker, Leon ORCID: https://orcid.org/0000-0001-5867-4663 and Memon, Fouzia (2018) Influence of maternal factors and mode of induction on labour outcomes: a pragmatic retrospective cohort study. Journal of Obstetrics and Gynaecology, 38 (7). pp. 946-949.

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Abstract

Since recent research indicates that other modalities are at a minimum non-inferior to the NICE-recommended hormonal agent prostaglandin E2 (PGE2), a retrospective cohort study was conducted on 1971 consecutively induced singleton pregnancies. The multinominal regression showed that the odds ratio (OR) for vaginal delivery with balloon-mediated labour induction (84% vaginal deliveries; OR 1.6; 95% CI 0.7–3.5) is similar to the PGE2 agents propess (81%; OR 1.2; 95% CI 0.68–1.98) and prostin (79%; OR 0.99; 95% CI 0.55–1.79) when using a triple multi-agent induction as a reference. On the other hand, combining the propess and prostin (60% vaginal deliveries; OR 0.45; 95% CI 0.21–0.96) and attempting quadruple combinations of the induction modalities (56%; OR 0.37; 95% CI 0.16–0.85) yields significantly poorer outcomes. However, compared to the known factors associated with increased caesarean section rates, such as an increased maternal age, nulliparous pregnancies and a history of caesarean section, the differential impact of different induction modalities appears as less pronounced.

Item Type:	Article
Journal / Publication Title:	Journal of Obstetrics and Gynaecology
Publisher:	Taylor & Francis
ISSN:	1364-6893
Departments:	Professional Services > Marketing & Student Recruitment
Depositing User:	Anna Lupton
Date Deposited:	02 Mar 2018 13:42
Last Modified:	12 Jan 2024 19:31
URI:	https://insight.cumbria.ac.uk/id/eprint/3646

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