Stereotactic MR imaging for planning neural transplantation: a reliable technique at 3 Tesla?

Donovan, Tim, Fryer, T., Peña, Alonso, Watts, C., Carpenter, T. Adrian and Pickard, J.D. (2003) Stereotactic MR imaging for planning neural transplantation: a reliable technique at 3 Tesla? British Journal of Neurosurgery, 17 (5). pp. 443-449. Full text not available from this repository.

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Abstract

The purpose of this study was to assess the accuracy of high field (3 Tesla) MR in target localization for stem cell transplantation. Three patients with Huntington’s disease were imaged with a stereotactic frame in place for both MRI and CT. Quality assurance procedures and manual shimming were performed before each MRI study to minimize image distortion. The images were fused using multi-modality rigid body image registration software. Image fusion demonstrated the MR images to be in agreement with CT to within 1.5 mm, as assessed by measuring the coordinates of markers on the frame and on the shape and size of the lateral ventricles. Target coordinates for transplantation were selected from the MR images. Postoperative imaging confirmed accurate graft placement.

Item Type: Article
Journal or Publication Title: British Journal of Neurosurgery
Publisher: Taylor & Francis
ISSN: ISSN 0268-8697 print/ISSN 1360-046X online
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Departments: Faculty of Health and Science > Medical and Sports Sciences > Health and Medical Sciences
Depositing User: Insight Administrator
Date Deposited: 03 Feb 2011 10:07
Last Modified: 02 Feb 2017 10:38
URI: http://insight.cumbria.ac.uk/id/eprint/318

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