Poor levels of agreement between serum and saliva testosterone measurement following exercise training in aging men

Hayes, Lawrence D., Sculthorpe, Nicholas, Herbert, Peter, Baker, Julien S., Hullin, David A., Kilduff, Liam P. and Grace, Fergal M. (2015) Poor levels of agreement between serum and saliva testosterone measurement following exercise training in aging men. Aging Male, 18 (2). pp. 67-70.

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Official URL: https://doi.org/10.3109/13685538.2015.1018158

Abstract

Testosterone (T) is a biologically important androgen that demonstrates a widely-known natural decline with advancing age. The use of salivary T (sal-T), as a determinant of systemic T, has shown promising results in recent years. However, the strength of the salivary-serum T relationship may be affected by measurement method and binding capacity with salivary proteins. The potential influence exercise may impact on this relationship is unstudied in aging men. Therefore, the aim of the present investigation was to examine the relationship of the delta change (D) in sal-T with Dserum T following six weeks exercise training. Fifteen sedentary (SED) males (aged 60.4 ± 5.0 years of age) and 20 lifelong exercising (LE) males (60.4 ± 4.7 years of age) were participated. Pearson’s correlation coefficient revealed sal-T did not correlate with total testosterone (TT), sex hormone binding globulin (SHBG), bioactive T (bio-T), or free T (free-T) at week 0 or week 6. Dsal-T did not correlate with DTT, DSHBG, Dbio-T or Dfree-T (r¼0.271, p¼0.180; r¼0.197, p¼0.335; r¼0.258, p¼0.205; and r¼0.257, p¼0.205, respectively). In conclusion, poor levels of agreement existed between saliva and serum measurements of T in response to exercise amongst aging men.

Item Type: Article
Journal or Publication Title: Aging Male
Publisher: Taylor & Francis
ISSN: 1368-5538
Departments: Faculty of Health and Science > Medical and Sports Sciences > Sports and Physical Activity > Sport
Depositing User: Lawrence D. Hayes
Date Deposited: 16 Mar 2016 15:52
Last Modified: 03 Aug 2017 17:36
URI: http://insight.cumbria.ac.uk/id/eprint/1837

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